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Production of anhydroretinol from all-trans-retinol catalyzed by retinol dehydratase. First, a sulfo group is transferred to all-trans-retinol (i) to form retinyl sulfate (ii). Loss of sulfate then generates a carbocationic intermediate (iii) that, in the confines of the enzyme active site, preferentially rearranges with loss of a proton to form anhydroretinol (iv).
