Table 1.
entry | olefin | yield %a (avg %) |
RCM-CM- chemoselective hydrogenation |
---|---|---|---|
1 | 64%b (86%) |
||
2 | 56% (82%) |
||
3 | 59%b (84%) |
||
4 | 40% (74%) |
||
5 | 52% (80%) |
||
6 | 65% (87%) |
||
7 | 43%c (76%) |
All reactions were performed using freshly distilled (over CaH2) FDT solvents
1,4-Benzoquinone is not used during RCM event.
Reaction was performed in CH2Cl2 purified by passing through basic Al2O3 and degassed by argon purging without any additives.