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. Author manuscript; available in PMC: 2013 Dec 10.
Published in final edited form as: Org Lett. 2012 May 8;14(10):2634–2637. doi: 10.1021/ol301007h

Table 1.

One-pot, sequential RCM/CM/chemoselective hydrogenation involving type I olefins.

entry olefin yield %a
(avg %)
RCM-CM-
chemoselective
hydrogenation
1 graphic file with name nihms-376255-t0006.jpg 64%b
(86%)
graphic file with name nihms-376255-t0007.jpg
2 graphic file with name nihms-376255-t0008.jpg 56%
(82%)
graphic file with name nihms-376255-t0009.jpg
3 graphic file with name nihms-376255-t0010.jpg 59%b
(84%)
graphic file with name nihms-376255-t0011.jpg
4 graphic file with name nihms-376255-t0012.jpg 40%
(74%)
graphic file with name nihms-376255-t0013.jpg
5 graphic file with name nihms-376255-t0014.jpg 52%
(80%)
graphic file with name nihms-376255-t0015.jpg
6 graphic file with name nihms-376255-t0016.jpg 65%
(87%)
graphic file with name nihms-376255-t0017.jpg
7 graphic file with name nihms-376255-t0018.jpg 43%c
(76%)
graphic file with name nihms-376255-t0019.jpg
a

All reactions were performed using freshly distilled (over CaH2) FDT solvents

b

1,4-Benzoquinone is not used during RCM event.

c

Reaction was performed in CH2Cl2 purified by passing through basic Al2O3 and degassed by argon purging without any additives.