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Glial fibrillary acidic protein (GFAP) immunostaining of mouse, rhesus monkey, and human astrocytes in cortex. Note striking differences in the sizes of mouse, monkey, and human astrocytes. Also note differences in the number and lengths of branches of astrocytes from mouse, monkey, and human being. Sizes of astrocytes increase with increasing complexity of brain function. Scale, 50 μm. Images are reproduced from Kimelberg and Nedergaard [133], with permission.
