. Author manuscript; available in PMC: 2014 Dec 1.

Published in final edited form as: Parkinsonism Relat Disord. 2013 Aug 6;19(12):10.1016/j.parkreldis.2013.07.018. doi: 10.1016/j.parkreldis.2013.07.018

Table 2.

Local peaks of clusters indicating significant gray matter loss in PD group compared to Controls. Results were considered significant at FWE (family-wise) corrected p < 0.05.

Anatomical Region	MNI coordinates^a			Z_max^b	Mean Volume^c		Volume Reduction (%) ^d
Anatomical Region	X	Y	Z	Z_max^b	Controls	PD	Volume Reduction (%) ^d
Frontal Cortex
R. Frontal Pole (BA 10,11)	14	56	−16	3.93	5431±629	5011±517	7.73
L. Frontal Pole (BA 10,11)	−26	62	−14	3.56	3384±418	3115 ±340	7.96
R. Medial Frontal gyrus (BA 10, 32)	8	50	−10	2.43	2297±332	2113±232	8.01
L. Medial Frontal gyrus (BA 10, 32)	−4	52	−14	2.67	1846±271	1699±196	7.97
Parieto-Occipital Cortex
L. Superior Parietal Lobe (BA 7)	−28	−58	54	2.57	152±27	138±23	8.84
R. Parieto-occipital junction (BA 18)	2	−80	28	3.06	4090±589	3525±439	13.81
L. Parieto-occipital junction (BA 18)	−2	−78	22	2.70	3139±518	2668±407	15.00
R. Lateral Occipital Cortex (BA 19)	24	−86	38	3.25	2570±346	2205±273	14.20
L. Lateral Occipital Cortex (BA 19)	−10	−88	38	3.91	2140±254	1808±247	15.53
R. Superior Occipital Cortex (BA 19)	16	−92	36	4.71	2382±330	2029±264	14.82
L. Superior Occipital Cortex (BA 19)	−12	−92	36	3.44	1621±241	1351±205	16.62

^a:

Coordinates of local maxima are given in MNI (Montreal Neurological Institute) standard space.

^b:

Z-scores of the local maxima.

^c:

Cluster extent is given in mean volume ± standard deviation (mm³).

^d:

PD patients’ relative gray matter volume reduction (in %), when compared to Controls. BA= Brodmann Area, R.: right, L.: left.