Table 3. Number and proportion of diagnosed cancers deemed clinically significant based on a variety of published definitions [23].
Definition | Criteria | Significant PCa, no. | Men with significant PCa (n = 105), % | Men with PCa deemed significant (n = 36), % |
---|---|---|---|---|
1 | Epstein criteria | 24 | 23 | 67 |
2 | Gleason 3 + 4 or MCL ≥4 mm | 26 | 25 | 72 |
3 | Gleason 4 + 3 or MCL ≥6 mm | 20 | 19 | 56 |
4 | Gleason≥7 | 22 | 21 | 61 |
5 | Gleason ≥8 | 11 | 10 | 31 |
PCa = prostate cancer; MCL = maximal core length.
Percentages in column 4 are based on the total population (n = 105), and those in column 5 are based on patients with PCa (n = 36). Clinically significant cancer based on definition 2.