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. Author manuscript; available in PMC: 2014 Dec 15.
Published in final edited form as: J Immunol. 2013 Nov 13;191(12):10.4049/jimmunol.1301329. doi: 10.4049/jimmunol.1301329

Figure 3. Nuclear RelA and RelB, and pro-inflammatory cytokine mRNA expression in CC10-NF-κBSR mice following exposure to HDM.

Figure 3

CC10-NF-κBSR mice, or WT littermate controls were exposed to PBS or HDM for 2 h. (A) Nuclear localization of RelA and RelB was assessed in lung tissues as described in Fig. 2. Images are representative results of two independent experiments with 5 mice/group, RelA/RelB, red; DNA, green; Nuclear RelA/RelB, yellow, scale bar=50μm. (B) Assessment of mRNA expression for IL-33, GM-CSF, CCL20, KC, MIP-2, and IL-6 in homogenized lung tissue. Data were normalized to cyclophilin and are presented as relative expression. Values reflect 6 mice/group/time point. * p< 0.05 (ANOVA) compared to the PBS group at the same time point. † p<0.05 (ANOVA) compared to WT mice exposed to HDM