Table 1. KATs involved into regulation of p53 and histones and their functional outcomes.

Acetyltransferase	Target residue in Histones	Functional outcome	Target residue in p53	Functional outcome
CBP/p300	H2A/B H3 H4K5,8,12,16	Transcriptional activation	K164, K370, K372, K373, K381, and K382	Stabilisation of p53 Increase p53-dependent transcription
PCAF	H3 H4	Transcriptional activation	K320	p21 induction
Tip60	Free histones H2AK5 H3K14 H4K5,8,12,16	Transcriptional activation Chromatin remodelling	K120	p53-dependent apoptosis
MOF	H4K16	Chromatin remodelling [127]	K120	p53-dependent apoptosis
MOZ	H2B, H3K14 H4K5,8,12,16 (in vitro) H3K9 (in vivo)	Transcriptional activation Chromatin remodelling	K120	p21 induction