Skip to main content
. 2013 Nov 21;9(10):1089–1098. doi: 10.7150/ijbs.7367

Figure 2.

Figure 2

Effects of Genistein on cell proliferation, apoptosis, and osteoblastic differentiation in the cultured hBMSCs. (A) Dose-dependent stimulation of cell growth in response to different concentration of Genistein (10-8~10-5 M) through BrdU incorporation assay; (B) No significant effects of Genistein (10-8~10-5 M) on cell apoptosis by measuring activation of caspase 3/7 activity; (C) Dose-dependent enhancement of ALP activity in response to different concentration of Genistein (10-8~10-5 M) at day 12; (D) Time-dependent acceleration of ALP activity in response to Genistein (10-6 M) treatment during 16 days of culture. Data are mean ± S.D. from triple independent experiments. E2 (10-8 M) served as a positive control. Values sharing the same superscript are not significantly different at P<0.05.