Table 2.
Comparison of mRNA levels and mean values of antigens expressions of ERs, aromatase and COX2 between studied endometrial cancers (EC) and normal endometrium tissues (control) using Q-RT-PCR study and immunohistochemistry (IHC study)
| Group | Q-RT-PCR study | IHC study | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Number | Mean | SD | P value | Number | Mean | SD | P value | ||
| ERα | EC | 48 | 85.92 | 258.58 | 0.0005 | 49 | 1.39 | 0.931 | ns |
| Control | 15 | 253.99 | 172.75 | 10 | 1.90 | 0.738 | |||
| ERβ | EC | 48 | 0.48 | 1.02 | 0.0005 | 51 | 0.88 | 0.887 | ns |
| Control | 15 | 0.88 | 0.81 | 10 | 1.60 | 1.174 | |||
| Aromatase | EC | 48 | 0.02 | 0.06 | 0.012 | 50 | 2.06 | 1.236 | 0.0005 |
| Control | 14 | 0.03 | 0.02 | 10 | 0.50 | 0.527 | |||
| COX2 | EC | 48 | 9.78 | 19.58 | ns | 51 | 1.71 | 1.006 | 0.011 |
| Control | 15 | 6.33 | 7.16 | 10 | 0.80 | 0.789 | |||