Figure 1.

Impaired motor skill learning in the fmr1 KO mouse. A, An illustration of the training box with a mouse reaching out for a food pellet through a narrow slit. The trained forelimb and the contralateral-trained hemisphere are marked. B, Average success rates during training for WT controls (black, n = 36) and fmr1 KO (blue, n = 38) mice. Both genotype and days of training affect success rate (p < 0.01, two-way repeated-measures ANOVA). C, There was no difference in the number of reaches performed by the KO and WT mice at any of the training days. mean ± SEM. *p < 0.05, **p < 0.01.