Table 1.

Neural abnormalities in humans associated with cocaine and METH/AMPH use

	Cocaine	METH/AMPH	Selected Reference
Baseline DA	↓	↓	[11], [36]
DA release	↓	↓	[17], [23]
DAT	↑	↓	[14], [33]
D1 receptors	ND	↑	[11], [34]
D2(D3) receptors	↓	↓	[18], [37]
D3(D2) receptors	↑	↑	[13], [38]
VMAT-2	↓	↓	[10], [30]
NET	↑	---	[7]
SERT	↑	↓	[8], [32]
Glutamate	↓	---	[9]

DA-dopamine, DAT-dopamine transporter, NET-norepinephrine transporter, SERT-serotonin transporter, VMAT-2-vasicular monoamine transporter, ND-no difference from controls, ---unknown.