Table-II.

Association between ERCC1 and RRM1 and response to chemotherapy

Expression level	N	%	Responders	%	Non-responders	%	OR(95% CI)	P value
Low ERCC1	145	49.3	65	42.8	80	56.3	-	-
High ERCC1	149	50.7	87	57.2	62	43.7	1.73(1.06-2.81)	0.02
Low RRM1	109	37.2	51	33.6	58	41.1	-	-
High RRM1	185	62.8	101	66.4	84	58.9	1.37(0.83-2.26)	0.19
Low ERCC1/Low RRM1	61	20.7	23	15.1	38	26.8	-	-
High ERCC1/ Low RRM1	48	16.3	28	18.4	20	14.1	2.32(0.98-5.39)	0.05
Low ERCC1/ High RRM1	84	28.6	42	27.6	42	29.6	1.65(0.81-3.43)	0.14
High ERCC1/ High RRM1	101	34.4	59	38.8	42	29.6	2.57(1.21-4.90)	0.01