Table-III.
Expression level |
Overall survival
|
||
---|---|---|---|
Median survival (95% CI, months) | Log-rank P | HR (95% CI) | |
Low ERCC1 | 11.7(2.6-15.3) | - | - |
High ERCC1 | 17.4(4.3-22.6) | 0.03 | 0.63(0.35-0.88) |
Low RRM1 | 13.5(3.2-16.4) | - | - |
High RRM1 | 15.4(3.6-18.4) | 0.08 | 0.77(0.42-1.54) |
Low ERCC1/Low RRM1 | 10.6(3.0-15.7) | - | - |
High ERCC1/ Low RRM1 | 16.2(3.2-18.9) | 0.06 | 0.67(0.36-1.03) |
Low ERCC1/ High RRM1 | 12.5(3.1-15.8) | 0.54 | 0.85(0.61-1.56) |
High ERCC1/ High RRM1 | 18.7(4.5-23.1) | 0.004 | 0.31(0.13-0.62) |