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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Curr Pharm Des. 2013;19(37):6594–6605. doi: 10.2174/1381612811319370004

Figure 1.

Figure 1

(a) Schematic for the folic acid receptor (FAR)-targeted drug delivery by a PAMAM dendrimer conjugate G5-FAn-(Drug)m. The conjugate presents a multivalent array of FA as a targeting ligand and carries cytotoxic drug molecules as payloads including methotrexate (MTX), paclitaxel, and doxorubicin; (b) Schematic for the FAR-targeted MTX delivery by a dendrimer conjugate G5-MTXn where MTX plays the dual-acting role as a targeting ligand as well as a cytotoxic agent. The figure is not drawn to scale.