8.5. |
The first-line chemotherapy for patients with advanced
ovarian cancer (II b-IV) must consist of carboplatin AUC5
and paclitaxel 175 mg/m2 for 3 h i. v. over a
total of 6 cycles, with one cycle every 3 weeks. |
A |
1++ |
Guidelines: 118, 119
Primary studies:
120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131
|
8.6. |
Additional therapy with bevacizumab can be considered in
patients with advanced ovarian cancer (IIIB-IV). |
0 |
1+ |
Primary studies: 132, 133
|
8.7. |
Changes in dose density or intensity should only be done as
part of a clinical trial. |
B |
1+ |
Guidelines: 2
Primary
studies: 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146
|
8.8. |
No maintenance or consolidation therapies must be carried out
after primary therapy has been completed.* |
A |
1+ |
Primary studies: 132, 133, 147, 148, 149, 150, 151, 152, 153, 154
|
8.9. |
Systematic recording of the patientʼs quality of life can be
helpful to identify difficulties during treatment. |
CC |