Figure 1.

Effect of propofol on LPS-induced TNF-α and IL-6 secretion. Macrophages were pretreated with dimethyl sulfoxide (DMSO) or 1 μM, 10 μM, 50 μM, and 100 μM propofol for 40 min and stimulated with 100 ng/mL LPS for 8 h. The concentrations of TNF-α and IL-6 in culture supernatants were measured by ELISA. Each value represents the means ± SD for n = 4. # and ∗ indicate statistically significant differences (P < 0.05) between propofol and LPS treated and LPS only treated groups, respectively.