Table II.
Sensitivity and Specificity at Adherence Cut-Points
Parent-reported adherence | EM adherencea |
|||||||
---|---|---|---|---|---|---|---|---|
Adherent | Non- adherent | Total n | Sensitivity % | Specificity % | PPV % | NPV % | Accuracy % | |
50% cut-point | ||||||||
Adherent | 39 | 1 | 40 | 100.0 | – | 97.5 | 0.0 | 97.5 |
Non-adherent | 0 | 0 | 0 | |||||
Total | 39 | 1 | 40 | |||||
60% cut-point | ||||||||
Adherent | 37 | 3 | 40 | 100.0 | – | 92.5 | 0.0 | 92.5 |
Non-adherent | 0 | 0 | 0 | |||||
Total | 37 | 3 | 40 | |||||
70% cut-point | ||||||||
Adherent | 34 | 6 | 40 | 100.0 | – | 85.0 | 0.0 | 85.0 |
Non-adherent | 0 | 0 | 0 | |||||
Total | 34 | 6 | 40 | |||||
80% cut-point | ||||||||
Adherent | 26 | 8 | 34 | 96.3 | 38.5 | 76.5 | 83.3 | 77.5 |
Non-adherent | 1 | 5 | 6 | |||||
Total | 27 | 13 | 40 | |||||
85% cut-point | ||||||||
Adherent | 25 | 9 | 34 | 96.2 | 35.7 | 73.5 | 83.3 | 75.0 |
Non-adherent | 1 | 5 | 6 | |||||
Total | 26 | 14 | 40 | |||||
90% cut-point | ||||||||
Adherent | 20 | 11 | 31 | 95.2 | 42.1 | 64.5 | 88.9 | 70.0 |
Non-adherent | 1 | 8 | 9 | |||||
Total | 21 | 19 | 40 |
Note. PPV = positive predictive value; NPV = negative predictive value; – = could not be calculated due to category frequencies.
aElectronic monitoring (EM) adherence used as the reference standard.