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Autosplenectomy is found in a patient with homozygous sickle cell disease. Axial T2wi SSFSE (a), coronal SSFP (b), and postcontrast axial 3D-GRE T1wi with fat suppression at the arterial phase (c). Note the small remnant of spleen and the diffuse diminished signal intensity of the hepatic parenchyma on both T1wi and T2wi as a result of iron deposition.
