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. 2007 Dec;83(8):266–275. doi: 10.2183/pjab/83.266

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© 2007 The Japan Academy

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 7. — Tissue distribution of poliovirus in mice after intravenous inoculation. (A) K_p,app values of [³⁵S]methionine-labeled MSM (a recombinant poliovirus Mahoney strain having the Sabin 1 derived capsid proteins) in various tissues were calculated in transgenic mice (vertical axis) and non-transgenic mice (horizontal axis) 5 h after the IV inoculation. (B) Transgenic mice were IV-injected with mAb p286 5 h before the IV inoculation of [³⁵S]methionine-labeled MSM.K_p,app values of MSM in various tissues were calculated (vertical axis) and transgenic mice pretreated with the mAb (horizontal axis) 5 h after the inoculation. (quoted from ref. 25).