Table 1.
Baseline characteristics by subject for the four study analysis groups.
| Characteristic | Index Cases (n=247) | Affected Family (n=358) | Controls (n=300) | Unaffected Family (n=64) | p-value |
|---|---|---|---|---|---|
|
| |||||
| 1 eye1 (OD) | 97 (39.3) | 21 (5.9) | 29 (9.7) | 1 (1.6) | <0.001 |
| 1 eye1 (OS) | 105 (42.5) | 48 (13.4) | 20 (6.7) | 7 (10.9) | <0.001 |
| 2 eyes1 | 45 (18.2) | 289 (80.7) | 251 (83.7) | 56 (87.5) | <0.001 |
|
| |||||
| Age2 | 68.9 ± 11.4 | 63.2 ± 12.8 | 71.2 ± 7.6 | 52.2 ± 13.6 | <0.001 |
|
| |||||
| Caucasian1 | 239 (96.8) | 352 (98.3) | 291 (97.0) | 64 (100.0) | 0.31 |
|
| |||||
| Male1 | 95 (38.5) | 98 (27.4) | 121 (40.3) | 22 (34.4) | 0.003 |
|
| |||||
| Diabetes (ever)1 | 31 (12.6) | 41 (11.5) | 31 (10.3) | 2 (3.1) | 0.18 |
|
| |||||
| FECD exam time (PM)2 (n=906) | 140 (57.1) (n=245) | 188 (53.7) (n=350) | 100 (40.0) (n=250) | 29 (47.5) (n=61) | <0.001 |
1
Results are presented using the frequency and percentage.
2
Results are presented using the mean and standard deviation.