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. 2013 Jul 15;20(6):549–565. doi: 10.1093/dnares/dst030

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© The Author 2013. Published by Oxford University Press on behalf of Kazusa DNA Research Institute.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.

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Figure 1. — Profiling of gene expression and DNA methylation in germ cells and stem cells. (A) PCA of the expression profiles of germ cells, stem cells and adult organs. ES_m (male ES cells), ES_f (female ES cells), EG_m (male EG cells), EG_f (female EG cells), 10.5m (PGCs from male E10.5 embryos), 10.5f (female E10.5 PGCs), 13.5m (male E13.5 PGCs), 13.5f (female E13.5 PGCs), 17.5m (male E17.5 PGCs), 17.5f (female E17.5 PGCs), P0.5m (spermatogonia from P0.5 neonates), P0.5f (oocytes from P0.5 neonates) and GS cells. Testis, thymus and brain were isolated from male adult mice. (B) PCA analysis of DNA methylation profiles of germ cells, stem cells and adult organs. (C) Hierarchical clustering of gene expression profiles. (D) Hierarchical clustering of DNA methylation profiles.