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. 2013 Nov 1;123(12):5284–5297. doi: 10.1172/JCI70877

Figure 8. Effect of voluntary exercise on CryABR120G×Atg7×tTA mice.

Figure 8

(A) Average running distance traveled by mice subjected to voluntary exercise for 7 months. (B) Kaplan-Meier survival curves of CryABR120G×tTA (n = 8) and CryABR120G×Atg7×tTA (n = 9) mice. (C–E) Echocardiography indices of (C) LV end-diastolic diameter, measured by LVIDs function, and LV function, measured by (D) %FS and (E) %EF, in male nonexercised and exercised mice (n = 8 per group). *P < 0.05 vs. nonexercised CryABR120G×tTA; #P < 0.05 vs. exercised CryABR120G×tTA; §P < 0.05 vs. nonexercised CryABR120G×Atg7×tTA, Tukey’s post-hoc test.