Table 2. First ten alternative solutions provided by ReacKnock for predicting 6-reaction deletions to produce succinate on the model E. coli_iAF1260 under aerobic condition with glucose Input = −10 mmol/g(Dw)h.
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
ACt2rpp | ATPS4rpp | ACGAMK | ACtex | 3HAD140 | ACtex | ACtex | ACtex | ACtex | ACtex |
ATPS4rpp | CBMKr | ACt2rpp | ATPS4rpp | ATPS4rpp | ATPS4rpp | ATPS4rpp | ATPS4rpp | ATPS4rpp | ATPS4rpp |
CO2tpp | CBPS | ATPS4rpp | CO2tex | CO2tpp | CO2tex | CO2tex | CO2tpp | CO2tex | CO2tpp |
PGL | CO2tpp | IDOND | G6PDH2r | FORtex | GND | PSERT | G6PDH2r | GND | G6PDH2r |
PSERT | PFL | PSP_L | PSP_L | FUM | PSERT | THD2pp | PGCD | PSP_L | PSP_L |
THD2pp | THD2pp | SUCDi | THD2pp | RPE | THD2pp | TKT1 | THD2pp | THD2pp | THD2pp |
0.108 | 0.109 | 0.129 | 0.108 | 0.128 | 0.108 | 0.108 | 0.108 | 0.108 | 0.108 |
10.24 | 9.73 | 9.13 | 10.24 | 9.35 | 10.24 | 10.20 | 10.24 | 10.24 | 10.24 |
The last two lines are growth rate and product rate respectively.