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. 2013 Dec 11;8(12):e81312. doi: 10.1371/journal.pone.0081312

Table 3. Patient characteristics according to IL28B rs8099917 genotype.

Characteristics TT (n = 179) TG or GG (n = 81) P-value*
Age (years) 56.1±11.4 54.5±11.4 0.295
Gender (male/female) 97/82 40/41 0.558
Body mass index (kg/m2) 22.8±3.5 23.6±3.7 0.094
HCV genotype (1/others) 127/52 65/16 0.153
HCV RNA levels (high/low) 162/17 73/8 0.895
PNPLA3 rs738409 (GG+GC/CC) 125/54 57/24 0.953
ALT (IU/L) 68.7±70.3 71.6±60.1 0.747
γ-GTP (IU/L) 43.0±39.9 63.4±72.1 <0.01
Platelet counts (×104/μL) 20.1±25.2 16.9±5.7 0.260
Total cholesterol (mg/dL) 177±31.1 172±27.7 0.215
AFP (ng/mL) 8.18±15.8 11.0±11.8 0.152
APRI 1.03±0.97 1.16±1.01 0.324
Fatty liver, yes/no 82/97 42/39 0.441
Cirrhosis, yes/no 23/156 14/67 0.449

± standard deviation. *P-value, between two groups with IL28B rs8099917 TT and with TG/GG by Student's t-test or chi-square test; HCV RNA levels, high: ≥5 logIU/mL; HCV RNA levels, low: <5 logIU/mL; ALT, alanine aminotransferase; γ-GTP, gamma-glutamyl transpeptidase; APRI, aspartate aminotransferase/platelet ratio index: AST (IU/L)/35/PLT (103/μL) ×100; fatty liver and hepatic cirrhosis were diagnosed by ultrasonography. Data are presented as mean