Table 3. Patient characteristics according to IL28B rs8099917 genotype.
Characteristics | TT (n = 179) | TG or GG (n = 81) | P-value* |
Age (years) | 56.1±11.4 | 54.5±11.4 | 0.295 |
Gender (male/female) | 97/82 | 40/41 | 0.558 |
Body mass index (kg/m2) | 22.8±3.5 | 23.6±3.7 | 0.094 |
HCV genotype (1/others) | 127/52 | 65/16 | 0.153 |
HCV RNA levels (high/low) | 162/17 | 73/8 | 0.895 |
PNPLA3 rs738409 (GG+GC/CC) | 125/54 | 57/24 | 0.953 |
ALT (IU/L) | 68.7±70.3 | 71.6±60.1 | 0.747 |
γ-GTP (IU/L) | 43.0±39.9 | 63.4±72.1 | <0.01 |
Platelet counts (×104/μL) | 20.1±25.2 | 16.9±5.7 | 0.260 |
Total cholesterol (mg/dL) | 177±31.1 | 172±27.7 | 0.215 |
AFP (ng/mL) | 8.18±15.8 | 11.0±11.8 | 0.152 |
APRI | 1.03±0.97 | 1.16±1.01 | 0.324 |
Fatty liver, yes/no | 82/97 | 42/39 | 0.441 |
Cirrhosis, yes/no | 23/156 | 14/67 | 0.449 |
± standard deviation. *P-value, between two groups with IL28B rs8099917 TT and with TG/GG by Student's t-test or chi-square test; HCV RNA levels, high: ≥5 logIU/mL; HCV RNA levels, low: <5 logIU/mL; ALT, alanine aminotransferase; γ-GTP, gamma-glutamyl transpeptidase; APRI, aspartate aminotransferase/platelet ratio index: AST (IU/L)/35/PLT (103/μL) ×100; fatty liver and hepatic cirrhosis were diagnosed by ultrasonography. Data are presented as mean