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Bacterial burden of BALB/c mice immunized with Class-C CpG (open circles) or PBS (solid circles) and challenged with B. mallei CSM001. Bacterial burden in the lungs (A), liver (B) and spleen (C) was determined in three mice per group per time point. To determine statistical differences, values were log transformed and then subjected to a paired two-tailed Student t test. Statistically significant value is designated * p < 0.05.
