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In vivo whole body imaging of BALB/c mice immunized with Class-C CpG or PBS and challenged with B. mallei CSM001. In vivo whole body bioluminescence and fluorescence images of Class-C CpG treated (A,B) and PBS treated (C) were taken at 24 h (A,C) and 72 h (B) post-infection. The intensity of emission is represented as a pseudocolor image. The luminescence and fluorescent images were then overlaid to visualize bacteria and neutrophil localization. (Overlay)
