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Histological analysis of lungs from BALB/c mice immunized with Class-C CpG or PBS and challenged with B. mallei CSM001. Representative images of Hematoxylin and Eosin stained mouse lungs sections from B. mallei-infected mice pre-treated with PBS (A–C) or class-C CpG ODN (D–F) at 24 (A,D), 48 (B,E) and 72 h (C,F) after challenge. Magnification 40x and scale bar = 100µM. Each panel is representative of the tissue pathology observed in three mice per treatment group.
