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. 2013 Dec 11;8(12):e82291. doi: 10.1371/journal.pone.0082291

Figure 4. Effects of restricted sleep on stimulated levels of cytokines and T helper 1/T helper 2 balance.

Figure 4

Means ± SE numbers of (A) interleukin (IL) 2, (B) IL-4 and (C) IL-2/IL-4 ratio during a baseline sleep-wake cycle (BL=sleep 23.00–07.00 h) and after five days with restricted sleep (RS=sleep 03.00–07.00 h). Grey lines illustrate adapted cosine curves of confirmed circadian rhythm during baseline; shaded area depicts sleep time during restricted sleep (03.00–07.00 h) and dashed box depicts baseline sleep (23.00–07.00 h).