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. 2013 Dec 11;8(12):e82567. doi: 10.1371/journal.pone.0082567

Figure 5. Proposed mechanism of interaction between C-terminal carboxyl-group and aromatic ring of tryptophan side-chain.

Figure 5

The specific interaction of the oxygen with the pyrrole ring, and the H-bond between the carboxyl oxygen and the α -NH amide of Trp, as shown in the figure, is speculative.