. Author manuscript; available in PMC: 2013 Dec 11.

Published in final edited form as: Adv Microbiol. 2012 Mar 1;2(1):10.4236/aim.2012.21005. doi: 10.4236/aim.2012.21005

Table 2.

MICs of mutant P. aeruginosa to polymyxin B.

Strains	MICs to polymyxin B (μg/mL)^a
PAO1 (phoQ::Tc/ΔpmrAB::Gm)	4
PAO1 (phoQ::Tc/ΔpmrAB::Gm)/pAU129	8
PAO1 (phoQ::Tc/ΔpmrAB::Gm)/pAU154	8
PAO1 (phoQ::Tc/ΔpmrAB::Gm)/pUCP18 (vector)	4
M38100B4 (ΔoprH-phoPQ::Gm)	8
M38100B4 (ΔoprH-phoPQ::Gm)/pAU146	16
M38100B4 (ΔoprH-phoPQ::Gm)/pAU147	16
M38100B4 (ΔoprH-phoPQ::Gm)/pAU148	16
M38100B4 (ΔoprH-phoPQ::Gm)/pUCP18 (vector)	8

MIC measurement repeated three times with identical results.

Note: pAU129, amino acid substitution (M292T) in PmrB; pAU154, amino acid substitutions (A247T; Y345H) in PmrB; pAU146, amino acid substitution (V260G) in PhoQ; pAU147, truncated-PhoQ; pAU148, amino acid substitution (H223R) in PhoQ (see details in the text).