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. 2013 Dec 11;8(12):e82585. doi: 10.1371/journal.pone.0082585

Table 1. Competitive cellular binding effect of heparin derivatives.

Heparin derivative Mean ± SD (%)
10 μg/ml 50 μg/ml
Tetrasaccharide 93.7 ± 10.9 86.7 ± 8.6
Hexasaccharide 86.4 ± 6.9 75.4 ± 10.9
Octasaccharide 54.5 ± 17.1 (**) 39.2 ± 11.9 (***)
Decasaccharide 33.4 ± 5.6 (**) 24.2 ± 3.5 (***)
de-2-O-SH 48.9 ± 8.6 (***) 41.4 ± 13 (***)
de-6-O-SH 47 ± 8.5 (***) 35.9 ± 8.7 (***)
de-N-SH 52.8 ± 4.5 (***) 35.5 ± 12.6 (***)
NAc-H 62.1 ± 1.3 (***) 55.5 ± 13.6 (***)
NAc-de-O-SH 95.8 ± 8.2 92.4 ± 9.8
HMWH 56.8 ± 4.4 (***) 28.9 ± 1.8 (***)
LMWH 42.6 ± 9.2 (***) 33.2 ± 4 (***)

The average amount of 0.4 μM wtECP bound to Beas-2B cells was set as 100% binding. **, P < 0.01; ***, P < 0.001