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. 2013 Dec 11;8(12):e82899. doi: 10.1371/journal.pone.0082899

Figure 7. Effect of the laser adjuvant on cell-mediated anti-influenza immune responses.

Figure 7

Systemic CD4+ helper T-cell responses were measured 4 days after challenge by re-stimulating 2×106 splenocytes with a nucleoprotein (NP) major histocompatibility class-II complex (MHC) or class-I influenza-specific peptide. Percentages of (A) CD4+IFN-γ+ (B) CD4+IL-5+ (C) CD4+IL-17+ and (D) CD8+IFN-γ+ T cells are shown. Also shown are representative FACS plots. Error bars show means ± s.e.m. Experimental and control groups: (A–D) n = 16, 18, 13, 20, 10 for no vaccine, vaccine i.d., vaccine i.d. + PW 532 nm, vaccine i.d. + CW 1064 nm, and vaccine + Alum i.d. vaccine groups, respectively.