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. 2013 Dec 11;8(12):e80520. doi: 10.1371/journal.pone.0080520

Table 1. Comparative data about wild type C57Bl/6 GNE+/+ and heterozygous C57Bl/6 GNE+/− mice.

C57Bl/6 GNE +/+ C57Bl/6 GNE +/+ P-value C57Bl/6 GNE +/− C57Bl/6 GNE +/− P-value
age (weeks) 24 80 24 80
number 9 7 10 12
creatine kinase [µmol/L*s] 191±106 (85–381) 287±156 (93–538) 0.05 231±97 (124–321) 356±97 (103–542) 0.05
total body weight [g ] 25.6±1.4 (23.7–27.8) 24.4 n.s. 28.2±3.5 (23.4–32.6) 24.7 n.s.
anterior tibial muscle weight [mg] 55.5±5.5 (48–62) 45.5±7.1 (37–58) n.s. 53.1±11.0 (35–66.5) 61.4±8.7 (51–66) n.s.
gastrocnemius muscle weight [mg] 145.4±16.0 (122–170) 126.6±25.5 (84–157) n.s. 153.9±21.2 (130–184) 151.9±31.6 (106–194) n.s.
quadriceps femoris muscle weight [mg] 190.6±21.2 (170–223) 187.9±28.1 (123–217) n.s. 210.0±41.2 (143–244) 207.3±31.3 (149–253) n.s.

±SD; range in parentheses; n.s., not significant. Data are mean

GNE +/+ and C57Bl/6 GNE +/− at 24 weeks and at 80 weeks. There was no statistical difference between the parameters in C57Bl/6