Table 2. Summary of Colorectal cancer linkage results with maximum observed HLODs greater than 2.
Study Group | No. Of Families | Linked Region | cM, SNP | Model | HLOD (α) |
---|---|---|---|---|---|
All families | 121 | - | - | - | - |
More than 3 affected | 27 | 9q31.1 | 102.68, RS1338121 | Recessive | 2.212 (0.66) |
Mean age at Diagnosis < 50 | 8 | 4p16.3 | 7.17, RS920683 | Recessive | 2.184 (1.00) |
17p13.2 | 11.51, RS884250 | Recessive | 2.086 (1.00) | ||
Families with Affected Sibs | 49 | Xp22.33 | 7.42, RS2306737 | Recessive | 2.486 (0.79) |