Figure 2. APOE Genotype, Sleep Consolidation, AD Pathology, and Cognitive Function Proximate to Death.
The model predicted composite global cognitive function proximate to death (A), Aβ pathology at autopsy (B) and neurofibrillary tangle density at autopsy (C) based on deceased participants are illustrated for hypothetical average APOE ε4+ and ε4− participants with poor (10th percentile), median (50th percentile), and good (90th percentile) sleep consolidation. Vertical bars indicate 95% confidence intervals.