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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: JAMA Neurol. 2013 Dec 1;70(12):10.1001/jamaneurol.2013.4215. doi: 10.1001/jamaneurol.2013.4215

Table 2.

Effect of Degree of Sleep Consolidation and Presence/Absence of the APOE ε4 Allele on the Risk of Incident AD

Effect on Risk of Incident AD
Predictor Model A Model B Model C Model D
Sleep Consolidation 0.84 [0.71–1.00]
p=0.05
0.84 [0.71–0.99]
p=0.04
0.83 [0.63–1.10]
p=0.19
APOE Genotype 2.21 [1.44–3.40]
p=<0.001
2.22 [1.44–3.42]
p<0.001
2.70 [1.51–4.83]
p<0.001
Sleep Consolidation x APOE Genotype 0.67 [0.46–0.97]
p=0.04

Hazard Ratio [95% Confidence Interval] p-values. Effects of sleep consolidation expressed per 1 standard deviation increase. Effects of APOE genotype expressed for presence vs. absence of the ε4 allele. All models adjusted for age at baseline, sex, and education