Table 2. Clinical Characteristics of the Participants According to Parathyroid Hormone Levels.
| Characteristic | Parathyroid Hormone Level | p-value | |
|---|---|---|---|
| ≤65 pg/mL (n=8435) |
> 65pg/mL (n=1338) |
||
|
| |||
| Age (years) | 45 ± 20 | 55 ± 21 | < 0.0001 |
|
| |||
| Sex (%) | 0.28 | ||
| Male | 49 | 47 | |
| Female | 51 | 53 | |
|
| |||
| Race/Ethnicity (%) * | < 0.0001 | ||
| Non-Hispanic white | 50 | 42 | |
| Non-Hispanic black | 21 | 31 | |
| Mexican American | 25 | 23 | |
| Other | 4 | 4 | |
|
| |||
| BMI (kg/m2) | 28 ± 6 | 31 ± 8 | < 0.0001 |
|
| |||
| Diabetes (%) | 8.5 | 12 | < 0.0001 |
|
| |||
| Hypertension (%) | 28 | 46 | < 0.0001 |
|
| |||
| 25-hydroxyvitamin D (ng/mL) | 22 ± 10 | 17 ± 8 | < 0.0001 |
|
| |||
| Calcium (mg/dL) | 9.5 ± 0.4 | 9.4 ± 0.4 | < 0.0001 |
|
| |||
| Phosphorus (mg/dL) | 3.8 ±0.5 | 3.7 ± 0.6 | < 0.0001 |
|
| |||
| Serum bicarbonate (mmol/L) | 25 ± 2 | 25 ± 3 | 0.86 |
|
| |||
| Serum uric acid (mg/dL) | 5.2 ±1.4 | 5.9 ± 1.6 | < 0.0001 |
|
| |||
| Estimated GFR (mL/min/1.73m2) | 98 ± 27 | 82 ± 31 | < 0.0001 |
|
| |||
| Diuretic use (%) | 10% | 25% | <0.0001 |
| Loop diuretics | 2% | 12% | |
| Thiazide diuretics | 7% | 12% | |
Values are expressed as means ± standard deviation or %=percent of patients; BMI=body mass index; GFR=glomerular filtration rate
*
The definition of race/ethnicity can be found at: http://grants.nih.gov/grants/guide/notice-files/NOT-OD-01-053.html
Conversion units: uric acid: mg/dL × 59.48 = μmol/L; calcium: mg/dL × 0.25 = mmol/L; vitamin D: pg/mL × 2.5 = pmol/L; phosphorus: mg/dL × 0.32 = mmol/L.