Table 3. Clinical characteristics of the participants according to stages of chronic kidney disease.
| Characteristic | Chronic Kidney Disease Stages MDRD- estimated GFR (mL/min/1.73m2) |
p-value | |||
|---|---|---|---|---|---|
|
| |||||
| ≥60 N=9001 |
45- 59 N=537 |
30-44 N=166 |
15-29 N=48 |
||
|
| |||||
| Age (years) | 43 ± 17 | 70 ± 11 | 73 ± 9 | 70 ± 10 | < 0.0001 |
|
| |||||
| Sex (%) | <0.0001 | ||||
| Male | 48 | 35 | 36 | 43 | |
| Female | 52 | 65 | 64 | 57 | |
|
| |||||
| Race/Ethnicity (%) | < 0.0001 | ||||
| Non-Hispanic white | 48 | 73 | 69 | 50 | |
| Non-Hispanic black | 23 | 10 | 20 | 23 | |
| Mexican American | 25 | 13 | 6 | 23 | |
| Other | 4 | 4 | 5 | 4 | |
|
| |||||
| BMI (kg/m2) | 29 ± 7 | 29 ± 5 | 30 ± 6 | 31 ± 6 | 0.003 |
|
| |||||
| Diabetes (%) | 7 | 21 | 36 | 51 | < 0.0001 |
|
| |||||
| Hypertension (%) | 25 | 67 | 72 | 8 | < 0.0001 |
|
| |||||
| 25-hydroxyvitamin D (ng/mL) | 22 ± 10 | 22 ± 8 | 20 ± 7 | 18 ± 7 | 0.004 |
|
| |||||
| Estimated GFR (mL/min/1.73m2) | 99 ± 24 | 53 ± 4 | 38 ± 3 | 24 ± 3 | < 0.0001 |
|
| |||||
| Serum uric acid (mg/dL) | 5.2 ± 1.4 | 6.2 ± 1.3 | 7.2 ± 1.2 | 7.9 ± 2.3 | < 0.0001 |
|
| |||||
| % with PTH >65 pg/mL | 11 | 31 | 54 | 88 | < 0.0001 |
Values are expressed as means ± standard deviation or %=percent of patients; BMI=body mass index; GFR=glomerular filtration rate