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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2013 Jul 17;65:10.1016/j.freeradbiomed.2013.07.011. doi: 10.1016/j.freeradbiomed.2013.07.011

Figure 7. In silico molecular modeling of 4-HNE modified Cys71 on huPTEN [60].

Figure 7

(A) Ribbon diagram demonstrating location of Cys71 and Cys124 (B) Electron density map demonstrating charge polarity (blue +, red −) and relationship of 4-HNE (slight blue stick) modified Cys71(yellow) and Cys124 (colored yellow-lower). (C) Electron density map demonstrating relative location of Cys124 following movement into the inactive state (4-HNE light blue stick, Cys71 is colored yellow CPK, Cys124 is colored green CPK)