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Schematic of nebulin (green), obscurin (blue), and titin (red) arrangement in the sarcomere. Nebulin is oriented with its C terminus in the Z-disc, Obscurin is oriented with its N-terminus in the M-line and its C-terminus bound to the sarcoplasmic reticulum, and titin is oriented with its N-terminus at the Z disc and its C-terminus at the M-line.
