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. 2013 Oct 29;109(12):3116–3124. doi: 10.1038/bjc.2013.646

Figure 1.

Figure 1

SiRNA effectivity in melanoma cell lines compared with ‘non-melanoma' cell lines. Inhibition of (A) cJun and (B) NRAS after 24 h treatment with si-cJun or si-NRAS in ‘non-melanoma' cell lines HEK and HeLa and melanoma cell lines Mel Im and Mel Ju. The average values of both groups are represented as dotted lines and pointed significant reductions of siRNA effectivities in melanoma cell lines. Statistical analysis was performed using the t-test, comparing ‘non-melanoma' and melanoma cell lines. *P<0.05.