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. 2013 Oct 29;109(12):3092–3104. doi: 10.1038/bjc.2013.655

Figure 4.

Figure 4

(A) 5-Fluorouracil chemoresistance. The proportion of cell viability is shown at 24, 48, and 72 h. (B) Different transfected TFK-1 cells were used for sphere formation and are shown at various time points (5, 10, 15, and 20 days). The expression of miR-200b and miR-200c (C) was detected during sphere formation and differentiation culture. The expression of NANOG, SOX2, TCF3, and OCT-4 mRNA during sphere formation and differentiation culture is shown in (D). The cell per sphere values (F) indicate the dimensions of the spheres. Sphere per 1000 cells (E) shows the capacity for sphere formation. All the data were compared with the data from the NC group.