Table 3. Association of interim MRI response after three courses of neoadjuvant chemotherapy with outcome measures.
| |
|
%
pCR |
%
pCR |
%
pCR |
|
|---|---|---|---|---|---|
| MRI response category | N | ypT0/is ypN0/+ | ypT0/is ypN0 | ypT0 ypN0 | RFS hazard ratio (95% CI) |
| Favourable |
164 |
10 |
4 |
2 |
Ref. |
| Unfavourable |
82 |
2 |
1 |
1 |
0.995 (0.42–2.33) |
| P-valuea | 0.04 | 0.43 | 1.0 | 0.99 |
Abbreviations: CI=confidence interval; pCR=pathologic complete remission; RFS=relapse-free survival; ypT0/is ypN0/+=no residual invasive tumour in the breast; ypT0/is ypN0=no residual invasive tumour in breast and lymph nodes; ypT0 ypN0=the absence of any tumour (invasive or non-invasive) in breast and lymph nodes.
a
pCR, Fisher's exact test; RFS and Cox regression analysis.