Table 3. Univariate Cox proportional hazards analysis of 54 SCC-MS patients.
| |
|
|
Overall survival |
Local progression-free rate |
||||
|---|---|---|---|---|---|---|---|---|
| Variable | No. of patients | Score | HR | P-value | 95% CI | HR | P-value | 95% CI |
|
Gender | ||||||||
| M | 43 | 0 | ||||||
| F |
11 |
1 |
2.25 |
0.233 |
0.63–14.32 |
5.25 |
0.039 |
1.07–94.86 |
|
Age (years) | ||||||||
| <63 | 33 | 0 | ||||||
| ⩾63 |
21 |
1 |
0.50 |
0.160 |
0.19–1.32 |
0.42 |
0.073 |
0.15–1.09 |
|
T stage | ||||||||
| T23 | 15 | 0 | ||||||
| T4a | 27 | 1 | 0.83 | 0.765 | 0.22–2.65 | 0.42 | 0.162 | 0.09–1.38 |
| T4b |
12 |
2 |
0.56 |
0.394 |
0.14–2.14 |
0.53 |
0.400 |
0.10–2.40 |
|
N stage | ||||||||
| 0 | 42 | 0 | ||||||
| Positive |
12 |
1 |
0.24 |
0.005 |
0.09–0.64 |
0.40 |
0.089 |
0.15–1.16 |
|
Middle nasal meatus | ||||||||
| No | 12 | 0 | ||||||
| Yes |
42 |
1 |
1.06 |
0.917 |
0.30–3.01 |
0.76 |
0.650 |
0.17–2.32 |
|
Ethmoid sinus | ||||||||
| No | 18 | 0 | ||||||
| Yes |
36 |
1 |
0.88 |
0.801 |
0.28–2.36 |
0.86 |
0.776 |
0.27–2.32 |
|
Dura and/or brain | ||||||||
| No | 3 | 0 | ||||||
| Yes |
51 |
1 |
0.36 |
0.239 |
0.10–2.32 |
0.94 |
0.953 |
0.19–17.00 |
|
Posterior wall and/or pterygoid fossa | ||||||||
| No | 16 | 0 | ||||||
| Yes |
38 |
1 |
1.40 |
0.514 |
0.48–3.68 |
0.75 |
0.601 |
0.21–2.11 |
|
Pterygoid process and/or sphenoid sinus | ||||||||
| No | 31 | 0 | ||||||
| Yes |
23 |
1 |
1.35 |
0.550 |
0.51–3.93 |
1.02 |
0.968 |
0.39–2.81 |
|
Nasopharynx and/or middle cranial fossa | ||||||||
| No | 3 | 0 | ||||||
| Yes |
51 |
1 |
0.80 |
0.776 |
0.22–5.10 |
1.87 |
0.507 |
0.38–33.74 |
|
Infratemporal fossa | ||||||||
| No | 30 | 0 | ||||||
| Yes |
24 |
1 |
1.16 |
0.760 |
0.45–3.21 |
0.85 |
0.730 |
0.32–2.25 |
|
Hard palate | ||||||||
| No | 30 | 0 | ||||||
| Yes |
24 |
1 |
0.80 |
0.644 |
0.30–2.13 |
0.40 |
0.064 |
0.14–1.05 |
|
Subcutaneous tissue | ||||||||
| No | 18 | 0 | ||||||
| Yes |
36 |
1 |
0.82 |
0.707 |
0.26–2.21 |
0.38 |
0.097 |
0.09–1.17 |
|
Skin of cheek | ||||||||
| No | 41 | |||||||
| Yes |
13 |
|
0.75 |
0.599 |
0.28–2.36 |
0.62 |
0.395 |
0.23–1.97 |
|
Cranial nerve other than V2 | ||||||||
| No | 52 | 0 | ||||||
| Yes |
2 |
1 |
0.33 |
0.359 |
0.07–6.00 |
0.40 |
0.433 |
0.08–7.20 |
|
Anterior orbital contents | ||||||||
| No | 37 | 0 | ||||||
| Yes |
17 |
1 |
1.84 |
0.265 |
0.65–6.59 |
1.60 |
0.396 |
0.56–5.70 |
|
Orbital apex | ||||||||
| No | 44 | 0 | ||||||
| Yes | 10 | 1 | 1.96 | 0.334 | 0.55–12.43 | 1.98 | 0.323 | 0.56–12.57 |
Abbreviations: CI=confidence interval; HR=hazard ratio; SCC-MS=squamous cell carcinoma of maxillary sinus.