Table 3. Pre-intervention level and changes in disease-specific QoL scores (EPIC), and general QoL scores (SF-12) in intervention and control groups at 4 weeks (pre-intervention) and 24 weeks after radiotherapy (post intervention) among 161 survivors with primary prostate cancer included in (RePCa) a prospective randomised rehabilitation study, 2010–2012 Odense, Denmark.
|
EPIC and SF-12 mean QoL (score 0–100)a |
|||||
|---|---|---|---|---|---|
| Intervention group, n=79 | Control group, n=82 | ||||
|
QoL |
Pre-intervention |
Difference at 6 months |
Pre-intervention |
Difference at 6 months |
|
| Mean (s.d.) |
4 Weeks after radiotherapy |
Between follow-up and pre-intervention |
4 Weeks after radiotherapy |
Between follow-up and pre-intervention |
Cohen's db |
|
EPIC domain | |||||
| Urinary irritative | 67.7 (18.7) | 17.6 (18.1) | 68.1 (18.7) | 11.6 (16.5) | 0.40 |
| Urinary incontinence | 82.5 (17.5) | 7.3 (14.9) | 82.2 (21.7) | 4.9 (15.8) | |
| Urinary sum-score | 73.5 (14.5) | 13.3 (13.9) | 73.1 (17.4) | 9.0 (12.9) | 0.34 |
| Bowel sum-score | 77.6 (19.9) | 9.7 (20.3) | 77.0 (20.0) | 7.6 (16.4) | |
| Sexual sum-score | 15.0 (19.5) | −1.3 (13.7) | 14.0 (20.1) | −4,1 (16.4) | |
| Hormonal sum-score |
71.6 (18.8) |
2.3 (13.2) |
72.8 (18.9) |
−2.8 (12.8) |
0.19 |
|
SF-12 domain | |||||
| PCS | 47.4 (8.3) | 1.9 (6.7) | 47.5 (9.0) | −1.7 (7.9) | 0.35 |
| MCS | 53.0 (8.7) | 2.3 (7.1) | 51.7 (9.6) | 2.3 (8.9) | |
Abbreviations: EPIC=Expanded Prostate Cancer Index Composite; MCS=Mental Component Summary; PCS=Physical Component Summary; QoL=quality of life; SF-12=Short-form-12.
a
Higher scores indicating better QoL. Note: SF-12 is standardised to the population normative values of the United States of America , with a mean score of 50 and a s.d. of 10.
b
Cohen's d effect size=group mean differences at patients post intervention divided by mean s.d.