Table 4.
Risk factors for negative outcome in severe sepsis and septic shock*, multivariate stepwise cox regression analysis.
| Hazard ratio | Lower limit | Upper limit | p-Value | |
|---|---|---|---|---|
| Age | 1.02 | 1.00 | 1.04 | 0.019 |
| Smoking | 1.62 | 0.97 | 2.71 | 0.063 |
| Cardiac heart failure | 2.21 | 1.12 | 4.36 | 0.022 |
| Liver disease | 1.93 | 1.00 | 3.74 | 0.050 |
| Immunosuppressiona | 2.41 | 1.50 | 3.87 | <0.001 |
| Lactate | 1.67 | 1.00 | 2.77 | 0.049 |
| SOFA score (day 1) | 1.12 | 1.05 | 1.20 | 0.001 |
*Patients from the current study and the two pooled comparative cohorts of severe sepsis and septic shock.
a According to APACHE II criteria.