Table 1.
Features of the Included Studies
| Patient Features |
Implant Features |
Surgical Intervention |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Study Design | Follow-up, mo | n | Age, y | Smokers, % | BL, n | FE, n | Location | Body Surface | Platform Surface | Detoxification Method | Grafting Material | Membrane | Submerge |
| 1: Khoury and Buchmann (2001) | |||||||||||||
| QE | 36 | 7 | 49.4 ± 5.2 | ND | 12 | 12 | ND | R | S | CHX(0.2%) + CA + H2O2 + NaCl | Auto | N | Y |
| 11 | 55.5 ± 14.1 | 20 | 20 | e-PTFE | |||||||||
| 7 | 48.6 ± 8.1 | 9 | 9 | Resorb | |||||||||
| 2: Deppe et al. (2007) a | |||||||||||||
| QE | 63 | 7 | ND | ND | 15 | 11 | ND | ND | ND | AA | Auto + ß-TCP | e-PTFE | Y |
| 9 | 17 | 13 | AA + CO2 laser | ||||||||||
| 3: Roos-Jansåker et al. (2007a) | |||||||||||||
| CS | 12 | 12 | 64.4 ± 6.0 | 66.7 | 16 | 16 | ND | S | S | H2O2 (3%) + NaCl | PCC | Resorb | Y |
| 4: Roos-Jansåker et al. (2007b) | |||||||||||||
| QE | 12 | 17 | 65.6 ± 7.4 | 70.6 | 29 | 29 | ND | R 1, S 28 | ND | H2O2 (3%) + NaCl | PCC | Resorb | N |
| 19 | 66.3 ± 6.8 | 68.4 | 36 | 36 | R 1, S 35 | PCC | N | ||||||
| 5: Schwarz et al. (2009) | |||||||||||||
| CS | 48 | 9 | 54.4 ± 12.5 | 0 | 9 | 9 | ND | ND | ND | PC + NaCl | AP | N | N |
| 11 | 11 | 10 | XG | Resorb | |||||||||
| 6: Schwarz et al. (2010) | |||||||||||||
| CS | 12 | 27 | 48.5 ± 14.6 | ND | 9 | 9 | 7 mand, 2 max | R | S | IP + CC + NaCl | XG | Resorb | N |
| 9 | 9 | 4 mand, 5 max | R 8, S 1 | ||||||||||
| 9 | 9 | 5 mand, 4 max | R | ||||||||||
| 7: Roccuzzo et al. (2011) | |||||||||||||
| CS | 12 | 12 | 60 ± 8.8 | 16.7 | 12 | 12 | 7 mand, 5 max | R | S | PC + EDTA gel + CHX + NaCl | XG | N | N |
| 14 | 59.9 ± 7.0 | 14.3 | 14 | 14 | 8 mand, 6 max | R | |||||||
| 8: Aghazadeh et al. (2012) | |||||||||||||
| RCT | 12 | 22 | 70.1 ± 6.2 | ND | 22 | 22 | ND | R 44, ND 1 | ND | H2O2 (3%) + NaCl | Auto | Resorb | N |
| 23 | 67.0 ± 7.5 | 70.0 | 23 | 23 | XG | ||||||||
| 9: Froum et al. (2012) | |||||||||||||
| CS | 49 | 15 | 58 | ND | 19 | 19 | ND | R | ND | GC + AA + NaCl + TCN + AA + CHX + NaCl + EMD + PDGF | XG or allograft | Resorb or SCTG | N |
| 23 | 32 | 32 | |||||||||||
| 10: Schwarz et al. (2012) | |||||||||||||
| RCT | 24 | 14 | 62.3 ± 10 | ND | 16 | 14 | ND | R 13, S 1 | ND | IP + PC + NaCl | XG | Resorb | N |
| 10 | 16 | 10 | R 5, S 4, ND 1 | IP + Er:YAG | |||||||||
| 11: Wiltfang et al. (2012) | |||||||||||||
| CS | 12 | 22 | 24-83 | ND | 36 | 36 | 26 mand, 10 max | ND | ND | IP + Etching gel | Auto + XG | N | N |
| 12: Wohlfahrt et al. (2012) a | |||||||||||||
| RCT | 12 | 16 | 65 ± 10 | 31.2 | 16 | 16 | ND | R | ND | TC + EDTA | PTG | N | Y |
The control arms were not listed in this table because they are not reconstructive procedures.
AA, air abrasive; auto, autogenous; BL, baseline; CA, citric acid (pH, 1); CC, carbon curette; CHX, chlorhexidine; CS, case series; EMD, enamel matrix derivatives; FE, final examination; GC, graphite curette; IP, implantoplasty; mand, mandible; max, maxilla; ND, not determined or reported; PC, plastic curette; PCC, phytogenic carbonate calcium; PDGF, platelet-derived growth factor; PTG, porous titanium granules; QE, quasi-experimental studies; R, rough; RCT, randomized controlled trial; resorb, resorbable membrane; S, smooth; SCTG, subepithelial connective tissue graft; TC, titanium curette; TCN, tetracycline; XG, xenograft.