. Author manuscript; available in PMC: 2014 Jul 15.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2013 May 9;86(4):10.1016/j.ijrobp.2013.03.020. doi: 10.1016/j.ijrobp.2013.03.020

Table 2.

Univariate and multivariate analysis for grade ≥2 late GU toxicity (n = 503)

		Multivariable analysis, P value
Variable	Univariable analysis, P value	Whole solid bladder	Contour wall bladder
Age	.059	.038^*	.047^*
Pretreatment urinary symptoms	.04^*	.051	.027^*
Hypertension	.32	.39	.40
Stroke	.84	.78	.70
TURP	.73	.72	.70
Heart disease	.24	.24	.19
AUHC (Solid whole bladder)	.047^*	.014^*
Bladder solid mean dose	.042^*	.012^*
V60 (solid whole bladder)	.056	.15
V62 (solid whole bladder)	.055	.11
V64 (Solid whole bladder)	.069	.21
V66 (solid whole bladder)	.05	.34
V68 (solid whole bladder)	.036^*	.33
V70 (solid whole bladder)	.0068^*	.13
AUHC (contoured bladder wall)	.043^*		.024^*
Bladder wall mean dose	.039^*		.022^*
V60 (contoured bladder wall)	.056		.56
V62 (contoured bladder wall)	.055		.96
V64 (contoured bladder wall)	.052		.70
V66 (contoured bladder wall)	.05		.60
V68 (contoured bladder wall)	.034^*		.82
V70 (contoured bladder wall)	.0068^*		.49

Abbreviations: AUHC = area under the histogram curve; DVH = dose–volume histogram; DWH = dose–wall histogram; GU = genitourinary; TURP = transurethreal resection of prostate; VXX = volume receiving XX Gy.

P<.05.